Sounds of Science

Bringing Dialysis to Remote Regions: Chris Atwater and the Bridge of Life

Charles River — Tue, 03 Mar 2026 08:00:00 +0000

Patients who need kidney dialysis live all over the world - even in some of the remotest regions. They need updated equipment, trained healthcare staff, and lots of clean water. Chris Atwater, Director of Technical Operations at the nonprofit Bridge of Life, helps bring hope to these areas. He has traveled to six continents for his life's work, using skills he learned as a United States Marine and the education he acquired for this role.

If you are interested in learning more about challenges facing dialysis patients in remote areas, check out this video we made about services in the Australian bush.

Hope in Action: Fighting SPG50 and Beyond with Elpida Therapeutics

Charles River — Tue, 17 Feb 2026 08:00:00 +0000

When Terry Pirovolakis learned his son had an ultra-rare neurodegenerative disease, SPG50, he refused to accept “no options.” What started as a desperate search for hope became Elpida Therapeutics, a nonprofit driving gene therapy innovation for multiple rare diseases. In this episode, Terry shares the remarkable journey from diagnosis to clinical trials, the power of partnerships, and why urgency matters when every day counts.

Show Notes

From Mystery to Medicine: The Science Behind a Mother’s Search | Podcast
Taking a Customized and Collaborative Approach to Therapeutic Development | Podcast
Rare Disease Research for Drug Development | Charles River
Rare Disease | Charles River
Discovery | Charles River
Beyond The Diagnosis

Turning Hope Into Action: Fighting USP7-Related Diseases

Charles River — Tue, 03 Feb 2026 08:00:00 +0000

What happens when a rare disease diagnosis turns life upside down? In this episode of Sounds of Science, host Mary Parker sits down with Bo Bigelow, Amber Freed, and David Fischer to explore the breakthroughs, challenges, and human stories behind Hao-Fountain Syndrome. From a father’s fight for his daughter Tess to cutting-edge drug repurposing screens, discover how science, advocacy, and community are rewriting the future for families worldwide.

Show Notes

Rare Disease | Charles River

Vital Science Podcast: Strength in Numbers
Rare Disease Research for Drug Development

Foundation for USP-7 Related Diseases

Stronger Every Day Podcast

Beyond The Diagnosis

Charles River — Tue, 20 Jan 2026 08:00:00 +0000

When Patricia Weltin’s daughters were diagnosed with Ehlers-Danlos Syndrome after years of uncertainty, she turned her frustration into a global movement. In this episode of Sounds of Science, Patricia shares the story behind Beyond the Diagnosis, a powerful art and advocacy initiative that uses portraiture to humanize rare diseases and inspire empathy in medical professionals, students, and communities around the world. From medical schools to courthouses and even Parisian galleries, the traveling exhibit is reshaping how we see children with rare diseases—not as diagnoses, but as vibrant individuals with stories worth telling. Tune in to hear how Patricia’s mission is bridging the gap between science and compassion, and how you can help carry it forward.

Show Notes

From Mystery to Medicine: The Science Behind a Mother’s Search | Podcast
Taking a Customized and Collaborative Approach to Therapeutic Development | Podcast
Rare Disease Research for Drug Development | Charles River
Rare Disease | Charles River
Discovery | Charles River
Beyond The Diagnosis

Planning For Potential Pandemics: The Coalition for Epidemic Preparedness Innovations

Charles River — Tue, 06 Jan 2026 14:37:34 +0000

As we all learned in 2020, getting ahead of the next major pandemic is a matter of global concern. For the Coalition for Epidemic Preparedness Innovations, or CEPI (cepi.net), it is their reason for existing. Joining me for this conversation are Valentina Bernasconi, Head of Laboratory Science for CEPI, and Marie-Eve Poupart, Lead Scientist In Charles River’s Immunology department. Together we discuss CEPI’s progress so far, how Charles River is contributing to the cause, and how we can plan for the unknown Disease X while simultaneously handling current outbreaks of deadly diseases like Ebola, Marburg, Nipah virus, Lassa Fever, and chikungunya.

Breathing New Life into Toxicology: Human-Relevant Models in Action

Charles River — Tue, 16 Dec 2025 13:00:00 +0000

What if we could predict how chemicals affect human lungs without using animals? In this episode of Sounds of Science, Mary McElroy, Head of Discovery Toxicology and Pharmacology at Charles River, joins us to explore a groundbreaking collaboration with MatTek Life Sciences. Together, they’re pioneering human-relevant, non-animal models that could revolutionize inhalation toxicology. From 3D lung tissues to computational dosimetry, discover how science is catching its breath and moving toward a safer, more ethical future.

Show Notes

Fighting For Liam - The Leston's Story

Charles River — Tue, 02 Dec 2025 05:00:00 +0000

For this episode I am joined by Megan and JC Leston, two parents who are fighting for their son Liam. The oldest of their five children, Liam was born with the rare Cri du Chat or 5p- syndrome. Through years of perseverance, they have created the Cri du Chat Research Foundation and started a movement to find a cure not only for Liam, but for all families affected by this genetic disease.

Listen now to hear their story, and find out more about their work and how you can help at www.criduchatresearch.org.

Choosing Wisely: The Ethics, Science, and Emotion Behind Species Selection

Charles River — Tue, 18 Nov 2025 13:00:00 +0000

What if one decision could make or break your drug’s success? Join Charles River’s Sarah Gould as she unpacks the high-stakes, emotion-filled world of species selection—and why it’s about so much more than science. Discover how this critical choice shapes safety, speeds development, and drives innovation in today’s evolving research landscape.

Show Notes

Supporting Mental Health for Veterans and First Responders: A Sabbatical Story

Charles River — Tue, 04 Nov 2025 13:30:09 +0000

Charles River scientist Nicole Hoekstra, herself a US Navy veteran, used her employer-supported sabbatical to help out local Oklahoma based nonprofit Inner Circle Mental Health, which focuses on aiding veterans and first responders who are struggling with their mental health. I am joined by Nicole and ICMH founder Kate Cooper to discuss what this service means to both of them, how we can support family who are reluctant to accept help, and how the COVID pandemic impacted the mental health of first responders.

Little Monsters: How Microbes Manage At The Edge of Existence

Charles River — Tue, 21 Oct 2025 01:00:00 +0000

Ryan Cox from Microbial Solutions joins us to discuss the curious creatures living at the edges of life – from microbes pulled from the MIR space station to antibiotic resistant bacteria festering in shark mouths. Meet these and many more on this episode!

From Mystery to Medicine: The Science Behind a Mother’s Search

Charles River — Tue, 07 Oct 2025 08:00:00 +0000

When Dalila Sabaredzovic’s sons were diagnosed with an ultra-rare genetic condition, she faced more questions than answers. But through resilience, advocacy, and the power of collaboration, her family's story has become a beacon of hope in rare disease research. In this deeply moving episode of Sounds of Science, Dalila shares her journey from despair to discovery—and how a global village of scientists came together to pursue a personalized treatment that could change everything.

Show Notes

Regulations and Realities in Lab Animal Use

Charles River — Tue, 16 Sep 2025 12:43:40 +0000

Chris Magee, Head of Policy and Media for the UK advocacy group Understanding Animal Research, and Naomi Charalambakis, Director of Science Policy & Communications at the US based advocacy group Americans for Medical Progress, joins me to discuss new directives from the US FDA and the EU regarding lab animal use. Join us to cover the realities of lab animal use today, as well as the history or public misinformation dating back before Charles Darwin!

Off-Target, On-Point: How Retrogenix® Reduces Risk and Animal Use

Charles River — Tue, 02 Sep 2025 08:00:00 +0000

In this episode of Sounds of Science, learn how the Retrogenix® platform is reshaping drug development by identifying off-target risks earlier, reducing animal use, and gaining traction with regulators—now as part of the FDA’s ISTAND pilot program. Guests Nick Brown and Mark Aspinall-O’Dea from Charles River Discovery Services share real-world insights on their role in advancing NAMs and supporting safer, faster therapeutic development.

Show Notes

Dirt-y Jobs: Ecotoxicology Testing

Charles River — Tue, 05 Aug 2025 03:00:00 +0000

How do researchers keep our dirt clean? How can earthworms, duckweed, birds and bees help us ensure environmental safety? Find out now by listening in with our experts from Charles River's Hungarian site - Szabolcs Gáty and David Esdaile.

A Saudi Startup Makes History in Gene Therapy

Charles River — Tue, 15 Jul 2025 05:00:00 +0000

For this exciting conversation, I am joined by NanoPalm CEO and co-founder Dr. Ali Alhasan and by Charles River Executive Director Ramin Baghirzade, who joins us to talk about Charles River’s incubator program for startups like NanoPalm. Alhasan and his co-founder, Dr. Samar Alsudir, began NanoPalm to help reach rare disease patients who could benefit from advanced gene therapies. NanoPalm is the first company to conduct a gene therapy clinical trial in Saudi Arabia, with plans for many more treatments in the works. Listen now to learn about the trial, Charles River’s incubator program, and about the current state of biotech startup in Saudi Arabia.

From Tumor to Treatment: How PDX Models are Powering Cancer Breakthroughs

Charles River — Tue, 01 Jul 2025 08:00:00 +0000

What if a mouse could help shape the future of cancer treatment? In this episode of Sounds of Science, host Mary Parker speaks with Julia Schüler, DVM, PhD, Research Director and Therapeutic Area Lead for Oncology at Charles River. Julia shares how patient-derived xenograft (PDX) models—often described as “avatars” of human tumors—are transforming preclinical oncology research. From preserving tumor heterogeneity to improving translational relevance, PDX models are accelerating the discovery of more effective, personalized therapies. Tune in as we explore how these advanced models are driving innovation across the drug development pipeline—from target discovery to clinical trial design.

Show Notes

Microbiologists in Manufacturing

Charles River — Tue, 17 Jun 2025 12:20:17 +0000

Join me, Charles River’s Miriam Guest, and independent consultant Vanessa Figueroa as we tackle the role of a microbiologist in drug manufacturing. Who is keeping patients safe from contamination, and how are they making sure our life saving drugs are not contaminated? How is manufacturing like yoga? Find out by listening now!

Behind the Breakthroughs: Rethinking Animal Research with the 3Rs

Charles River — Tue, 03 Jun 2025 08:00:00 +0000

What happens when cutting-edge science meets compassion? In this episode of Sounds of Science, host Mary Parker sits down with two pioneers reshaping the future of research: Elizabeth Nunamaker, Executive Director of Global Animal Welfare and Training at Charles River, and Dr. Megan LaFollette, Executive Director of the 3Rs Collaborative. From digital biomarkers to environmental health monitoring, they reveal how innovation and collaboration are redefining what’s possible in animal welfare — and raising the bar for ethical, high-quality research. Tune in to explore the tools, strategies, and bold ideas driving meaningful change across the scientific community.

Show Notes

Advancing Alternatives | Charles River

Evolving Animal Welfare: Science, Ethics, and Innovation | Sounds of Science
Can You Practice High-quality Science and 3Rs? | Eureka Blog
Animals in Research | Charles River
Research Models & Services | Charles River

What Makes a Virus Contagious?

Charles River — Tue, 20 May 2025 00:01:00 +0000

Join Charles River experts Sandy Kimber, Charlotte Cumper, and Claire Richards from our Portishead site for a discussion on what makes some viruses more contagious than others, how viruses can trick your immune system, and how vaccines can affect viral spread.

The Journey of Susannah’s Personalized ASO

Charles River — Tue, 06 May 2025 08:00:00 +0000

When Luke Rosen's daughter was diagnosed with KIF1A—a rare, progressive neurological disorder—he didn't wait for answers. He and his wife built a community, launched a nonprofit, and became a driving force in rare disease research. In this episode, Luke shares how patient-led science accelerates treatments and reshapes what’s possible for families like his.

Show Notes 

Sounds of Science - N=1 Episode
Charles River | Rare Disease

Charles River | Rare Disease for Drug Discovery

Charles River | ASO Screening Services
Personalized ASO Provides Improvement for a Girl with KAND< an Ultra-rare Disease

SCA3: A Family Affair

Susannah's Superhero Story

Evolving Animal Welfare: Science, Ethics, and Innovation

Charles River — Tue, 15 Apr 2025 08:00:00 +0000

Are we on the brink of a major shift in research? In this episode of Sounds of Science, Charles River experts challenge traditional approaches, exploring cutting-edge innovations that enhance animal welfare while driving scientific breakthroughs.

From revolutionary non-animal testing methods to advanced behavioral management strategies, we uncover how ethical care leads to better data and faster drug discovery. Tune in to discover how science, compassion, and innovation are shaping the next era of drug development.

Show Notes 

Animals in Research | 3Rs

Alternative Methods Advancement Project

CHARTER Program for Lab Animal Welfare

Advancing Responsible Science

Cancer Vaccines, Then and Now

Charles River — Tue, 01 Apr 2025 12:14:15 +0000

Did you know that the first attempt at a cancer vaccine was all the way back in the 1800s? I am joined by Charles River experts Louise Brackenbury, Dan Rocca, and Mike Templin to discuss the fascinating science behind therapeutic cancer vaccines.

Clarification: Coley’s Toxin is not a vaccine in the traditional sense, but a compound developed by William Coley in the 19th century as a treatment for cancer, and is considered a precursor to modern cancer immunotherapy.

All About Spheroids

Charles River — Tue, 18 Mar 2025 13:42:14 +0000

Spheroids are three dimensional cell models that can mimic some organs, tumors, and other biological systems for drug testing. Like organoids and organs-on-a-chip, spheroids are breaking in to drug development as a promising alternative to animal models. I am joined by Madhu Lal Nag, MBS PhD from the 3D in vitro model company InSphero, to discuss the development and future potential of these tiny cellular machines.

Ep. 89: Rethinking Toxicology: The Future of NAMs in Agrochemicals

Charles River — Tue, 04 Mar 2025 08:00:00 +0000

The agrochemical field has long relied on animal models to evaluate the safety and efficacy of substances, but there’s a growing demand to adopt new alternative methods (NAMs) that can further the industry while reducing the need for animal testing. However, questions remain as to their long-term viability.

Join Robert Landsiedel, Vice President of Experimental Toxicology and Ecology, and Susanne Kolle, Research Coordinator of Experimental Toxicology and Ecology at BASF, as they explain the benefits of NAMs, how they comply with the 3Rs principle, and the role collaboration is playing to push NAMs as a viable alternative to animals.

Show Notes

Alternative Methods

AMAP Strategic Partnerships

Animals in Research

Modernizing Drug Development

Agrochemical Testing Service for Approvals

Chemical Testing Services

Charles River Laboratories Announces Development of Nonclinical Virtual Control Groups with Sanofi to Reduce the Use of Animals

Charles River Laboratories, in Collaboration with MatTek Corporation, Awarded Grant from the Foundation for Chemistry Research and Initiatives to Advance Research Alternatives

Ep. 88: The Epidemiology of Cancer

Charles River — Tue, 18 Feb 2025 12:35:27 +0000

How can genetic, geographic, and social considerations effect outcomes for Black women with cancer? To answer this question, I am joined this week by Dr. Lauren E. McCullough, Associate Professor in the Department of Epidemiology at the Rollins School of Public Health, and Julia Schueler, Research Director Therapeutic Area Lead Oncology for Charles River. Dr. McCullough is also one of the lead researchers for the American Cancer Society’s VOICES of Black Women initiative, which will track the health of participants over several years to gain insight into health considerations for Black women. For more information on how to enroll, please visit voices.cancer.org.

Ep. 87: Taking a Customized and Collaborative Approach to Therapeutic Development

Charles River — Tue, 04 Feb 2025 08:00:00 +0000

The N=1 Collaborative is changing the way we view drug development. Their specialty is creating customized therapies tailored to individual patients, paving the way for a unique approach that can leave long-lasting impacts on those with ultra-rare diseases.

Join us as Executive Director Hugh Hempel discusses the origins of N=1, the collaborative effort it takes to advance customized therapies down the pipeline, and what the future holds for the field of individualized medicine.

Show Notes

n=1 Collaborative

Rare Disease | Charles River

Rare Disease Research for Drug Development

Repurposing Drugs for Rare Disease

S4 E07: Free For Life: The Story of N-Lorem Foundation

Ep. 85: The Next Generation of Drug Development

Charles River — Tue, 21 Jan 2025 08:00:00 +0000

Artificial intelligence and machine learning are launching a new era in drug development. By integrating these technologies, researchers can get their life-saving therapies to patients faster thanks to more accurate data and efficient processes.

Join us as Brian Roche, General Manager of Charles River’s integrated toxicology site in Kansas, as he discusses the advantages of using these advanced technologies, how their being leveraged across multiple platforms, and what role they play in shaping the future.

Show Notes

New Integrated Toxicology Site

Kansas Site

Unlocking the Promise of Integrated Toxicology: A Tour Through the Lab of the Future

Meeting at the Intersection of Technology and Scientific Innovation

Ep. 84: A Family's Fight Against Batten Disease

Charles River — Tue, 07 Jan 2025 13:58:33 +0000

David and Karen Kahn were overjoyed when they welcomed twins Amelia and Makenzie in 2010. However, it wasn't long before they realized their girls were different. Since getting their Batten disease diagnosis, they have worked tirelessly to find a treatment not only for their girls, but for kids around the world, with the help of researcher Dr. Michelle Hastings. Listen to their story now, and learn more about their mission at www.forebatten.org.

Ep. 83: NAMs: The Future of Research?

Charles River — Tue, 17 Dec 2024 08:00:00 +0000

As researchers look for ways to reduce the need for animals in their studies, new alternative methods (NAMs) are an intriguing route to capture crucial safety data and help advance drug discovery and development – specifically, virtual control groups (VCGs).

Join Steve Bulera, CVP and Chief Scientific Officer for Safety Assessment and Toxicology at Charles River, as he discusses how VCGs can be a viable alternative to research models, what it would take for the industry to widely accept NAMs, and how they can revolutionize research for the future.

Show Notes

Virtual Control Groups

Sounds of Science E73: Virtual Control Groups

Modernizing Drug Development with Virtual Control Groups

Virtual Control Groups: A Data-Driven Novel Method

Revolutionizing the Future of Safety Studies

Charles River Laboratories Announces Development of Nonclinical Virtual Control Groups with Sanofi to Reduce the Use of Animals

Ep. 82: Taking PrEP to the Next Level

Charles River — Tue, 03 Dec 2024 14:17:45 +0000

Dr. Jared Baeten, Senior Vice President of Clinical Development and Virology Therapeutic Area Head at Gilead Sciences, joins me to discuss the incredible advancements in pre-exposure prophylaxis (PrEP) treatments in honor of World AIDS Day. What if a twice yearly shot could replace a daily pill? Listen now to learn more!

Ep. 81: Biomedical Engineering: The Future of Research?

Charles River — Tue, 19 Nov 2024 04:00:00 +0000

As researchers continue to look for new ways to test therapeutics in vitro, the field of biomedical engineering is offering new microphysiological systems that can reduce the need for animal models. Hear from Jeffrey Borenstein, Director of the Biomedical Engineering Centre at Draper, as he explains how it works, ways to expedite its access, and the benefits they will ultimately bring to patients.

Show Notes 
 

The Coming of Age of Organ-on-a-Chip technology

Sounds of Science E76: Multi-Organ Chip Systems

Charles River Joins Consortium to Advance Organ-on-a-Chip Technology

Bold New Approached: The Future of Organoid Intelligence

Organoids Evolve from Academic Marvel to Industrial Tool

Ep. 80: Diversity in Veterinary Medicine

Charles River — Tue, 05 Nov 2024 15:51:51 +0000

I am joined by Raphael (Ralph) Malbrue, Director & Attending Veterinarian, Center for Comparative Medicine, University of Virginia; and Christina (Winnie) Winnicker, Executive Director for Laboratory Animal Medicine for Charles River. Both bring a fresh perspective to the questions of how to improve diversity in veterinary medicine, how to inform new graduates of previously unconsidered career paths in lab animal medicine, and what kind of specialties are in demand in the industry now.

Ep. 79: Painting a Picture of Hope to Treat PACS2

Charles River — Tue, 15 Oct 2024 04:00:00 +0000

Piotr Kosla, founder of the PACS2 Research Foundation, joins us to discuss his personal motivation to develop the first treatment for Development and Epileptic Encephalopathy 66 (PACS2 Syndrome), how cell painting assays are being used to repurpose a treatment for this condition, what the future holds for research in this area, and how you can help contribute to his mission.

Show Notes

Ep. 78: Starting Over After Cancer

Charles River — Tue, 01 Oct 2024 13:20:44 +0000

Lisa Sharp, Project Coordinator for Charles River, joins us to discuss her COVID lockdown experience. Right at the beginning of the pandemic, just weeks apart, both she and her husband were diagnosed with cancer. Sadly, he didn't make it. While Lisa and their daughter faced the worst, she decided to make big changes to her life and career. Listen now to hear her story.

Ep. 77: Ophirex: Biting Back

Charles River — Tue, 17 Sep 2024 13:45:00 +0000

Imagine you’re exploring the great outdoors when, out of nowhere, you feel the fangs of a snake – a poisonous snake – breaking through your skin. Medical care is nowhere in sight, so you’re left with the terrifying prospect of venom slowly infecting your body’s critical functions.

This is the reality that roughly five million people face annually. Over 500,000 of which either die or are permanently maimed or suffer long-term cardiovascular/neurological impairments.

However, Drs. Rebecca Carter and Matt Lewin are working to change that. Their work at Ophirex revolves around further developing Varespladib, a repurposed drug, as an accessible and affordable oral treatment to instantly combat venomous snakebites. By ingesting a small tablet or capsule, victims can buy time to seek out more advanced care, giving them a better chance to limit complications and prevent death.

Join us as we explore the impacts snake venom has on the body, how Drs. Carter and Lewin discovered Varespladib, how collaborations and partnerships have benefited their development of this treatment, and what can be done to improve its accessibility, especially in remote areas of the world.

Show Notes

Ophirex Lifesaving Antidotes

Antivenoms -_World Health Organization

Interventions for the Preventing Reactions to Snake Venoms - National Institute of Health

Ep. 76: Multi-Organ Chip Systems

Charles River — Tue, 03 Sep 2024 12:04:01 +0000

I am joined by Dr. Kacey Ronaldson-Bouchard from Columbia University, who is an expert on linking organs on a chip together to form models of human systems. Can these models replace animals? Can they save time and money in drug development and safety testing? Find out now when you listen to this podcast!

Ep. 75: Porcine Kidneys for Human Transplant

Charles River — Tue, 06 Aug 2024 13:36:18 +0000

Mike Curtis, president and CEO of eGenesis, and transplant surgeon Dr. Leonardo Riella join me to discuss the ongoing research into pig kidney to human transplants. How can a porcine kidney be genetically modified to be safe for a human? Listen now to find out more.

Ep. 74: One Patient's Sickle Cell Story

Charles River — Tue, 09 Jul 2024 13:33:06 +0000

Felicia Samuel has worked for Charles River for years, but recently the work she contributes to has taken on a new meaning. Her daughter will be part of a clinical trial to receive one of the brand new sickle cell treatments, with the potential to drastically change her own and her family's lives. She joins me to discuss the details of this amazing but involved gene therapy process, and how working for one of the companies that contributed to this treatment's research makes her feel. You can read more about it here: https://www.criver.com/eureka/crispr-silences-sickle-cell

Ep. 73: Virtual Control Groups

Charles River — Tue, 04 Jun 2024 12:31:19 +0000

What if we could replace mouse model control groups with a virtual equivalent? What would that mean for drug development in terms of cost, time, and animal model reduction? To answer, I am joined by Charles River associate director Laura Lotfi and Guillemette Duchateau-Nguyen from F. Hoffmann-La Roche Ltd, Pharmaceutical Sciences - Roche Innovation Center Basel. Listen now to learn how close we are to replacing some physical models with 1's and 0's.

Ep. 72: Artificial Intelligence in Cell and Gene Therapy

Charles River — Tue, 07 May 2024 00:01:00 +0000

Alex Sargent, Director of Process Development at Charles River in our Cell and Gene Therapy department, joins me to discuss the work he and his partner put into developing an algorithm to make his job faster and easier. How can you train a computer to accurately sift through the mountains of data generated in drug development? Listen now to find out!

Ep. 71: Cellular Agriculture - Lab Grown Meat of the Future

Charles River — Tue, 02 Apr 2024 12:54:04 +0000

There have been many articles recently about cellular agriculture, or lab-grown meat products. But what happens when a company takes a practical approach to this science fiction concept? Joining me are Charles River's Steven Miklasz from our Biologics Testing Solutions team; and Ramsey Foty, Scientific Director for Fork & Good, a cultivated meat company, to discuss how the sausage is made!

Ep. 70: Benjamin Oakes and the Promise of CRISPR

Charles River — Tue, 05 Mar 2024 11:48:16 +0000

This month I am joined by Benjamin Oakes, scientist, entrepreneur, and co-founder of Scribe Therapeutics. He studied at UC Berkeley, working in the Doudna Lab and Savage Lab during the earliest days of CRISPR. We discuss his personal vision for the future of CRISPR, encouraging advances in the field, and the first ever drug approval for a CRISPR based therapy.

Ep. 69: Past and Future of Endotoxin Testing

Charles River — Tue, 06 Feb 2024 13:52:41 +0000

Norm Wainwright and Foster Jordan have been immersed in the field of limulus amebocyte lysate (LAL) testing for decades, and have seen the progress and refinement of this crucial safety test. With the 20th anniversary of Charles River's Endosafe Cartridge and the recent introduction of recombinant alternatives, we look back at the past and future of endotoxin testing.

Ep. 68: Looking Ahead in 2024

Charles River — Thu, 04 Jan 2024 14:07:54 +0000

I am joined by four experts in their field to discuss what will be hot in rare diseases, drug discovery, artificial intelligence, and animal models in 2024.

Ep. 67: A Rare Diagnosis

Charles River — Tue, 05 Dec 2023 14:16:29 +0000

Molly Dupre, a lab assistant at Charles River's Reno site, was recently diagnosed with Niemann-Pick Type B/ Acid Sphingomyelinase Deficiency. After years of waiting, doctor's visits, and tests, she could finally put a name to the condition that flared up after the birth of her son. But what came next? She joins me to tell her story.

Ep. 66: When Drug Candidates Miss the Mark: Off-Target Liability

Charles River — Tue, 07 Nov 2023 13:51:40 +0000

Senior Principal Scientific Advisor Stan Spence joins me to discuss off-target liability: what happens when a drug misses its target? What are the risks to the patient if the off-target effects aren't caught early? Has there ever been an example of an off-target effect being beneficial to the patient? Find out here!

BONUS: Life After Cancer With Rachel and Susan

Charles River — Tue, 10 Oct 2023 18:47:35 +0000

Rachel Kiserow and Susan Desmond have joined us year after year as part of Eureka's Breast Cancer Roundtable. This year, they wanted to share what happens after - after the treatments, after remission - life after cancer.

Ep. 65: The New England Compounding Center Tragedy

Charles River — Tue, 03 Oct 2023 12:33:17 +0000

For this episode, I am joined by Charles River's Doug Botkin and Pure Microbiology's Abby Roth to discuss the 2012 NECC meningitis outbreak. Doug and Abby bring their background in microbiology to explain how it happened, and how we can prevent such tragedies in the future.

Ep. 64: State of Oncology Report

Charles River — Tue, 05 Sep 2023 14:57:41 +0000

Charles River experts Justin Bryans and Elizabeth Anderson join me for a spirited discussion of where we are now in oncology research. Could we ever see a world without cancer?

Ep. 63: Gene Therapy Manufacturing: Two Perspectives

Charles River — Tue, 01 Aug 2023 18:50:16 +0000

Manufacturing gene therapies is a hot topic in the pharma field, on both the supplier and the client ends. Joining me to discuss this issue is Charles River Associate Director of Gene Therapy, Andrew Frazer, and Purespring Therapeutics' VP of Chemistry, Manufacturing and Controls, Amanda Weiss.

Ep. 62: The Value of N-of-1 Research

Charles River — Wed, 05 Jul 2023 13:41:50 +0000

Dr. Lauren Black and Dr. Monkol Lek are both committed to the research and advancement of rare disease treatments. But when you are trying to treat just one patient, what can you learn that could help many more? We discuss the importance of n-of-1 studies, not just for that one patient and their families, but for anyone who might someday need a rare cure.

Ep. 61: Michael Hakeem on Recruiting Diversity Globally

Charles River — Thu, 01 Jun 2023 13:38:50 +0000

Through his own first-hand experience, Charles River Senior Director of Global Talent Acquisition Michael Hakeem knows the importance of diversity in hiring. He joins us this Pride Month to talk about his experiences and his insight into a thoughtful approach to recruiting for a company as large as Charles River.

Ep. 60: From Development to Manufacturing in Biologics

Charles River — Tue, 02 May 2023 18:08:37 +0000

Jesse McCool from Wheeler Bio and Ian Wyllie from Charles River's RightSource℠ program join me to discuss the manufacturing of biologics from both ends: getting from development to first in human, and quality control.

Ep. 59: Fungal Zombies, Fact and Fiction

Charles River — Tue, 04 Apr 2023 13:10:31 +0000

Mycologist Ziva Abraham discusses fungal detection and identification in cleanrooms, and whether the TV show The Last of Us portrays a realistic fungal zombie apocalypse.

Ep. 58: How To Be A Good Ally At Work

Charles River — Tue, 07 Mar 2023 15:26:32 +0000

This month I am joined by Romaine Wright, Program Manager for Learning and Development for Charles River, to discuss allyship in the workplace. How can we use whatever privileges we have to help our colleagues and build a more diverse workforce?

Ep. 57: Elise Lewis' Career in Toxicology

Charles River — Tue, 07 Feb 2023 14:01:51 +0000

This month I am joined by Dr. Elise Lewis, principal director of toxicology for Charles River's Horsham, Pennsylvania site. As a woman of color in the scientific field, she is passionate about mentoring the scientists of tomorrow.

She can also be seen in this interview with Fox 29 Philadelphia: https://www.fox29.com/video/902459

Ep. 56: In Vitro Vs. In Vivo

Charles River — Tue, 03 Jan 2023 14:48:04 +0000

In vivo models have been the drug safety standard for as long as there have been drug safety standards. With mounting data proving the worth of in vitro models, could there be a future where we will not need in vivo? I am joined by Anjli Venkateswaran, Director of Strategic Partnerships for Charles River, to discuss this trending topic.

Ep. 55: Looking Back at 75 Years of Charles River

Charles River — Tue, 06 Dec 2022 13:25:23 +0000

This year Charles River celebrated its 75th anniversary. To help me reminisce about how far the company and science in general have come in that time, I invited Chief Commercial Officer Bill Barbo to chat. He started at Charles River in 1982 as a scientist, and has seen the company grow and change along with advances in science.

Ep. 54: Avian Flu in 2022

Charles River — Tue, 01 Nov 2022 12:20:47 +0000

This year saw the worst spread of avian influenza yet, with fall showing another surge as migratory birds make their way south for the winter. Could an avian influenza vaccine be on the horizon for the United States? I spoke with Wayne Collins and Nastassja Ortega from Charles River’s Avian Services, and David Swayne, Lab Director for the USDA specializing in Exotic & Emerging Avian Viral Diseases Research to find out.

Ep. 53: Dr. Faqi - From Scientist to Ambassador

Charles River — Tue, 04 Oct 2022 01:00:00 +0000

I am joined by a very special guest - Dr. Ali Said Faqi, former employee of Charles River and current Congressman for Somalia. In 2013 his career path changed when he decided to accept an appointment as Somalia's ambassador to the European Union, but he still makes time for science.

Ep. 52: A Royal Recognition for Mental Health

Charles River — Tue, 06 Sep 2022 12:49:26 +0000

Charles River senior account manager Brad Gartland experienced a great personal tragedy when his father took his own life in 2016. Driven by the loss, Brad worked to establish a safe place for men like his father to talk, helping them feel less alone. Listen now to learn how Brad's efforts caught the attention of the British Royal family.

Ep. 51: Gene Therapy with Dr. Kathrin Meyer

Charles River — Tue, 02 Aug 2022 00:01:00 +0000

Dr. Kathrin Meyer from the Center for Gene Therapy at Nationwide Children's Hospital joins me to discuss the current state of gene therapy research - where we are now, and how far we have left to go.

Ep. 50: COVID, Monkeypox, and Avian Flu: Viruses 2022

Charles River — Tue, 05 Jul 2022 12:37:35 +0000

I am joined by consulting physician Dr. Peter Matos, an expert on viral spread through his work at the U.S. Department of Defense Global Emerging Infection Surveillance and Response System, to discuss the various viruses making their way through the world as of now.

Ep. 49: Sex Parity in Animal Research

Charles River — Tue, 07 Jun 2022 00:01:00 +0000

Sex discrimination is not just something that happens with people. In many animal studies, males have historically been used more often than females, resulting in a significant sex bias that has snowballed since we started using mice and rats in research. Liz Nunamaker, Director of Animal Welfare for Charles River, joins me to discuss what this bias means for animals and patients.

Ep. 48: Lab Animal Diets and Doing Good Science

Charles River — Tue, 03 May 2022 12:53:58 +0000

Graham Tobin is one of the most noted experts on laboratory animal diets, writing several definitive texts on the subject. He joins me to discuss how a lack of attention to animal nutrition can impact research, from reproducibility to reliability.

Ep. 47: Killing Tumors From the Inside Out

Charles River — Mon, 04 Apr 2022 19:59:51 +0000

We talk with Oliver Jonas, the Scientific Founder of Kibur Medical, about his research on implantable devices designed to distribute cancer drugs directly into tumors. Kibur is a strategic partner of Charles River, and these tiny devices could help doctors narrow down the best therapies for each individual patient.

Ep. 46: Three Young Women Battle ALS and Stereotypes

Charles River — Mon, 28 Feb 2022 11:49:32 +0000

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a degenerative neurological disease most often associated with older while males. However, it is not exclusive to them, and obtaining a diagnosis as a young woman can be tricky. The women of Her ALS story are patients and spokespeople who are trying to change that by sharing their stories with the world. Listen now to hear their stories, and learn more at heralsstory.org.

Ep. 45: A Possible Cure for Diabetes

Charles River — Tue, 01 Feb 2022 00:01:00 +0000

Dr. Jeffrey Millman joins me and my colleague Laura Gee to discuss his work on a potential cure for Type 1 diabetes. Laura, who is herself a Type 1 diabetes patient, shares her perspective on living with diabetes and what a cure could mean for her everyday life. Using cellular replacement therapy, The Millman Lab works towards a diabetes cure.

Ep. 44: Vaccine Vials and COVID Innovations

Charles River — Tue, 04 Jan 2022 13:56:32 +0000

Lawrence Ganti, president of SiO2 Materials Science, joins me to discuss ramping up production of his innovative vaccine vials to distribute COVID-19 vaccines. We also discuss how the pandemic in general affected scientific innovation and medical product manufacturing, and what it could mean for the future of medicine.

Ep. 43: Two Pioneers in HIV Activism and Research

Charles River — Wed, 01 Dec 2021 00:01:00 +0000

For World AIDS Day, I interviewed two pioneers in HIV/AIDS activism and research: Dr. Kenneth Mayer, Medical Research Director of Fenway Health and a professor of medicine, global health and population at Harvard; and Professor Gregg Gonsalves from the Yale School of Public Health. Ken has been part of AIDS research almost from the beginning, and Gregg is a passionate advocate for underrepresented patients. Both have devoted their careers to furthering HIV/AIDS awareness and public health responsiveness.

Ep. 42: Neuroscience During COVID: A Conversation With Two Scientists

Charles River — Tue, 02 Nov 2021 12:53:20 +0000

This year's Society for Neuroscience meeting was supposed to be in person, but with COVID cases still high, moved to virtual. Charles River scientists Carina Peritore and Toni Ahtoniemi join me to discuss what else is new in the field of neuroscience, and how COVID has affected research over the past two years.

Ep. 41: Is There a Human Lyme Vaccine on the Horizon?

Charles River — Tue, 05 Oct 2021 12:56:24 +0000

With global warming affecting the tick population, the time is right to try again with a human Lyme disease vaccine. I talk with Dr. Richard Marconi, professor at Virginia Commonwealth University's Department of Microbiology and Immunology, about his research into ticks, Lyme, and the promise of a human vaccine.

Ep. 40: Boosting the Signal for Vaccines

Charles River — Tue, 07 Sep 2021 17:26:34 +0000

In this episode, I speak with Dr. Peter Matos about vaccine boosters past and present. We discuss a brief history of vaccine booster research, how we arrived at the current recommended vaccine schedule, and what the future may hold for COVID vaccine boosters.

At the time of posting, the US Centers for Disease Control and Prevention (CDC) only recommends COVID boosters for immunocompromised people, though the US government announced broader rollout through the fall and winter. The World Health Organization (WHO) currently recommends focusing on first dose rollout for populations that have not gotten access yet, and says that "introducing booster doses should be firmly evidence-driven and targeted to the population groups in greatest need."

Stay updated on your region's booster policies.

Ep. 39: Marcus Gerald – From Patient to Scientist

Charles River — Tue, 03 Aug 2021 13:24:43 +0000

Scientist Marcus Gerald experienced first hand what it feels like to be a patient at a young age. Now he helps children by researching the Developmental and Reproductive Toxicology (DART) of new drugs. In this episode he tells us about his experiences as a young Black man in science, and how he turned his early childhood experiences into his passion.

Ep. 38: PhD Candidates on the Front Lines of COVID

Charles River — Tue, 06 Jul 2021 14:05:31 +0000

COVID impacted everyone differently, including early career scientists who found their work resources diverted to COVID research. One such scientist is doctoral candidate Daisy Hoagland from the Icahn School of Medicine at Mount Sinai, whose earlier work on viruses made her a valuable contributor to COVID research. But what did it do to her career plans? Listen now to find out.

Ep. 37: Ambassadors of Science

Charles River — Tue, 01 Jun 2021 13:02:31 +0000

Elaine Duncan and Alan Mukuvare are early career scientists who understand the importance of scientific mentors. They themselves have benefited from inspiring STEM mentors, and are now giving back to their local communities through the UK's STEM Ambassador Programme. Listen now, especially if you or someone you know are thinking about getting into a STEM field.

Ep. 36: Ziva Abraham, Master Mycologist

Charles River — Tue, 04 May 2021 12:54:13 +0000

For this episode, I am joined by Ziva Abraham, CEO of the pharmaceutical consulting company Microrite. Ziva grew up in India, and fell in love with fungi while studying in college. Her passion has taken her all over the world, dispensing knowledge and mentoring a new generation of young women scientists.

Ep. 35: COVID and Climate Change

Charles River — Tue, 06 Apr 2021 13:27:03 +0000

In honor of Earth Day 2021, we speak with Corporate Sustainability experts Gregg Belardo and Erik Mohn about the lessons learned from the COVID-19 pandemic. Some of the effects of stay-at-home orders could be seen from space, but did they have any impact on climate change? Listen now to learn more.

Ep. 34: Drug Approval in the New Normal

Charles River — Tue, 02 Mar 2021 01:00:00 +0000

Scientific Advisor Mike Templin joins us to discuss what drug developers have learned from working with the FDA during the pandemic. Where can we improve the relationship between science and government regulations? Find out now by listening to this episode.

Ep. 33: A Father's Fight

Charles River — Tue, 02 Feb 2021 14:46:43 +0000

In honor of Rare Disease Month, we are joined by Terry Pirovolakis from CureSPG50.org. Terry's son Michael was born with the ultra-rare SPG50 disease. Listen now to hear their story.

Ep. 32: How to Keep Computers Happy, Chemistry Edition

Charles River — Tue, 05 Jan 2021 01:00:00 +0000

Yugal Sharma, Ph.D., from CAS and David Clark, Ph.D., from Charles River join us to discuss machine learning in chemistry. We discuss the importance of organizing big data to avoid creating a data dump, and how machine learning can speed up drug discovery.

Ep. 31: Rare Isn’t Rare: A Conversation With Antonio

Charles River — Tue, 01 Dec 2020 01:00:00 +0000

Antonio Maltese, a senior studying political science in Virginia, is passionate about advocating for the rare disease community. He belongs to the community himself twice over, with a diagnosis of Huntington’s Disease and osteonecrosis. He speaks with Charles River scientists Lauren Black and David Fisher about his studies, their research, and how scientists and patients can help each other.

Ep. 30: New Partnerships in the New Normal

Charles River — Tue, 03 Nov 2020 11:00:00 +0000

COVID-19 wreaked havoc with academic labs - students were sent home, campuses were closed, and research projects were delayed or cancelled. Given the critical value of academic research, especially for preparing for or even preventing future pandemics, how can we avoid this situation in the future? Emory University's George Painter and Charles River's Joe Cornicelli discuss one potential solution.

Ep. 29: Farm Pharma

Charles River — Tue, 06 Oct 2020 13:15:54 +0000

Simon Chapleo, an expert in plant metabolism, joins us to discuss agrochemical safety testing and the difficulties of cultivating banana plants in Scotland.

Ep. 28: Building the Building Blocks of Life

Charles River — Tue, 01 Sep 2020 06:00:00 +0000

Stem cells are a valuable tool in a drug researcher’s shed, but they are notoriously tricky and time consuming to grow. The biotech company Bit Bio hopes to change that by streamlining the process through their innovative cell reprogramming technology, making batches of cells ready at shorter notice. Bit Bio founder Mark Kotter and Charles River researcher Mariangela Iovino talk shop in this episode.

Ep. 27: My Rare Disease Does Not Define Me

Charles River — Tue, 04 Aug 2020 08:00:00 +0000

Gracie van Brunt – singer, songwriter, and rare disease survivor – joins us for a candid interview about her life, career, and experiences with growing up rare.

Ep. 26: From Rabbit to Crab to the Lab

Charles River — Tue, 07 Jul 2020 15:00:00 +0000

Foster Jordan knows a thing or two about horseshoe crabs, and isn't afraid to share his opinion! Listen now to learn about the future of endotoxin testing, and the potential pitfalls of recombinant technology.

Ep. 25: Tuning the CAR T

Charles River — Tue, 02 Jun 2020 15:00:00 +0000

With chimeric antigen receptor T-cell (CAR T) therapy, patients’ own immune cells can be “souped up” and used as a cancer treatment. This immunotherapy and its variants are a promising area of research, with fascinating safety considerations. Listen now to learn about CAR T and TCR T from Sanne Holt, a biologist at Charles River.

Ep. 24: Collaborating to Cure Dementia

Charles River — Tue, 05 May 2020 11:35:00 +0000

Dementia is a tricky disease with no cure and precious few treatments. Join host Mary Parker and biologist Sarah Almond to learn about the Dementia Consortium, a public-private partnership determined to change this narrative through collaboration.

Ep. 23: What is Corporate Sustainability?

Charles River — Tue, 07 Apr 2020 10:00:00 +0000

What does corporate sustainability mean for the pharmaceutical industry? Gregg Belardo, Senior Director for Corporate Sustainability at Charles River, discusses the “no-brainer” policies that can help any company meet their green goals.

Ep. 22: Brother helping brother to cure Rare Disease

Charles River — Wed, 26 Feb 2020 14:00:00 +0000

Rich Horgan and Karen Morales from the nonprofit biotech Cure Rare Disease join host Mary Parker to discuss their work. Rich’s brother Terry has a rare form of muscular dystrophy, with no treatment available for adults. Rich founded Cure Rare Disease for his brother and patients like him, and after three years they are on the cusp of a breakthrough. Listen now to hear their story.

Ep. 21: This Medicine is for the Birds

Charles River — Tue, 04 Feb 2020 10:00:00 +0000

How can we keep animals healthy without antibiotics? In this episode we talk with avian expert Nastassja Ortega, who develops therapies to protect her chickens from disease through natural antibodies and vaccines. In the fight against antibiotic resistance, she is on the front lines, keeping her birds antibiotic-free.

Ep. 20 Tumors and their Entourage: Exploring the Tumor Microenvironment

Charles River — Tue, 07 Jan 2020 11:00:00 +0000

The tumor microenvironment (TME) insulates cancer from the body’s natural defenses. But like all defenses, the more we know about the TME, the easier it is for us to find chinks in the armor. Join host Mary Parker as she interviews Rhiannon Jenkinson, Director of Science for Discovery Services at Charles River’s Portishead site, about this fascinating and frustrating microworld.

Ep. 19: What’s Hot in 2020: AI and Biomarkers

Charles River — Tue, 03 Dec 2019 10:30:00 +0000

At the end of 2019, we wanted to take time to predict some of the hot research trends for the coming year. Many companies are taking up the challenge to reduce the time to market for vital therapies, so what are the cutting edge technologies that can make that goal a reality? I spoke with Charles River Discovery scientists Ian Waddell and Chris Hill about two of their favorite trends: AI and biomarkers in early drug discovery. How can these research tools get drugs to patients faster? Find out in this month’s episode!

Ep. 18: Speed vs. Safety: Rapid Approvals from the FDA

Charles River — Tue, 05 Nov 2019 08:00:00 +0000

Genome mapping has made personalized medicine achievable, but how can the FDA balance safety requirements with the speed that is necessary for desperate patients?

Introducing Vital Science

Charles River — Tue, 15 Oct 2019 08:00:00 +0000

Meet Gina Mullane and Chris Garcia, the hosts of Vital Science, a brand new podcast that shares the personal stories of those impacted by life science. Today, Gina and Chris are responsible for global marketing and sales operations, but they both began their careers in the lab. They've experienced the impact of life science from every angle, and use those experiences to tell the stories of patients, scientists, employees and advocates. Subscribe now and download the first episode on Tuesday, October 22nd!

Ep. 17: Noteworthy News on Neuroinflammation (Eureka's Sounds of Science)

Charles River — Tue, 01 Oct 2019 11:00:00 +0000

Central nervous system (CNS) diseases are well known for being tricky to treat and difficult to research. However, some researchers are getting excited about the possibilities of new research into neuroinflammation. For this episode of Sounds of Science we speak with Carina Peritore, product manager neuroscience discovery at Charles River. We will be discussing the relatively recent resurgence of research on neuroinflammation, which could hold the key to new therapeutic avenues for CNS diseases.

Ep. 16: The Quest to Cure Quincy (Eureka's Sounds of Science)

Charles River — Tue, 03 Sep 2019 12:30:00 +0000

Dr. Allyson Berent speaks with us about her work to find a cure for her daughter’s rare disease.

Ep. 15: Horseshoe Crabs: Natures First Historian (Eureka's Sounds of Science)

Charles River — Mon, 05 Aug 2019 18:56:28 +0000

Herodotus may be the first human historian, but to travel farther back in time we need our fossil friends, the horseshoe crab.

Ep. 14: Open Science vs. Free Market (Eureka's Sounds of Science)

Charles River — Tue, 02 Jul 2019 12:51:00 +0000

Can free data and for-profit research coexist?

Ep. 13: Biological Bandages for Animals (Eureka's Sounds of Science)

Charles River — Tue, 04 Jun 2019 13:10:00 +0000

How California veterinarian Jamie Peyton uses tilapia skins to heal four-legged burn victims, including those hurt in the California wildfires.

Ep. 12: Stage IV (Eureka's Sounds of Science)

Charles River — Tue, 07 May 2019 15:07:00 +0000

One woman describes the messy reality of living with stage IV cancer.

Ep. 11: Herd Immunity (Eureka's Sounds of Science)

Charles River — Tue, 02 Apr 2019 13:49:00 +0000

How vaccines can protect everyone if enough people get them. A conversation with microbiologist Ken Henderson.

Ep. 9: A Motion Capture Tool for Huntington’s (Eureka's Sounds of Science)

Charles River — Tue, 05 Feb 2019 14:21:42 +0000

A tool that seems inspired by Hollywood animation imagery allows us to accurately model and measure subtle movements in rodent models of CNS disease.

Ep. 8: Are You Listening? (Eureka's Sounds of Science)

Charles River — Tue, 08 Jan 2019 11:53:19 +0000

Medicines can be toxic to the ear, so where’s the regulatory guidance?

Ep. 7: Can We Stop NASH? (Eureka's Sounds of Science)

Charles River — Tue, 04 Dec 2018 17:05:38 +0000

The debilitating liver disease, a consequence of bad diets, is on the rise. So is the pipeline of drugs trying to arrest it.

Ep. 6: Cancer Conversations (Eureka's Sounds of Science)

Charles River — Fri, 02 Nov 2018 14:10:13 +0000

When communicating your concern to a cancer patient, words matter…a lot.

Ep. 5: CRISPR’s Rogue Tendencies (Eureka's Sounds of Science)

Charles River — Tue, 02 Oct 2018 17:37:13 +0000

CRISPR technology has enabled rapid advances in gene editing, but it also invites unintended consequences.

Ep. 4: David Hysong, Rare Disease Maverick (Eureka's Sounds of Science)

Charles River — Thu, 06 Sep 2018 18:29:18 +0000

David Hysong talks about a diagnosis that changed his life and professional direction.

Ep. 3: Raising the Platform in Cancer Immunotherapy (Eureka's Sounds of Science)

Charles River — Mon, 06 Aug 2018 15:06:01 +0000

One of the trickiest parts of drug discovery is moving from test tubes to animals. Here’s a way to not only pick up the pace of the process, but also the expectations for results.

Ep. 2: An Antibody Shield for Poultry (Eureka's Sounds of Science)

Charles River — Wed, 11 Jul 2018 19:01:24 +0000

Poultry products are going antibiotic free. Unfortunately for farmers, chickens won’t magically be healthy all the time.

Ep. 1: Germ Free Mice (Eureka's Sounds of Science)

Charles River — Mon, 07 May 2018 20:24:52 +0000

In the real world, we are constantly surrounded by countless living organisms. For the extraordinary germ-free mouse, this presents a problem. Join host Mary Parker and hear how Senior Manager Rich Morin and his team at Charles River’s transgenic facility are creating (literally) customized solutions to this problem.